From the site:
Design has emerged as one of the world's most powerful forces. It has placed us at the beginning of a new, unprecedented period of human possibility, where all economies and ecologies are becoming global, relational, and interconnected.
In order to understand and harness these emerging forces, there is an urgent need to articulate precisely what we are doing to ourselves and to our world. This is the ambition of Massive Change.
Interviews include architect Carol Burns, inventor Dean Kamen, nano-scientist Richard Smalley, cyberlawer Lawrence Lessig, author Stewart Brand and many more.
The site doesn't have an RSS feed, but the excellent interviews can be downloaded as MP3 files and listened to at your leasure.
More information is available at the Massive Change site.
